According to a study hospital patients in United States get an estimated half a million infections yearly, affecting more than 2 million patients. Pathogen transmission in healthcare settings is most often linked to contaminated hands of healthcare workers. Hand hygiene is one of the most important ways to prevent the spread of infections.

A multidimensional program focused on hand hygiene improvement is one of the highly recommended approaches by HICPAC and CDC. One of the most important aspects of hand hygiene guideline is use of waterless solutions such as liquids, gels or foams. Alcohol based rinses or gels containing emollients causes substantially less skin irritation and dryness than the soaps or antimicrobial detergents. Some studies show significant reduction in infections when clinical staff uses proper gloves and have awareness about appropriate technique for cleansing hands with alcohol based hand rub. Antimicrobial soap and water or alcohol based sanitizers must be used before and after direct contact with patients or medical equipments. Proper cleansing is essential when moving from a contaminated body site to a clean body site during patient care. Surgical hand scrub substantially reduces the number of microorganisms on intact skin.

Healthcare facilities play a very important role in meeting hygiene objectives by providing changes such as by placing dispensers  for alcohol-based hand rub and boxes of clean gloves of various sizes near the point of care. Surveys and studies indicate that the frequency of hand washing or antiseptic hand washing by clinical staff is affected by the accessibility of hand-hygiene products. Consistency, time required for drying, smell and color are key evaluation characteristics for high quality hand hygiene products for potential use in healthcare facilities.